Uterine Cancer is the most common malignancy of the female reproductive organs.

  • It is the 4th most common cancer in women behind breast, lung and colon cancers

Risk Factors:

  • No children or pregnancies
  • Early menarche
  • Late menopause
  • Obesity
  • Unopposed estrogen therapy

Signs or Symptoms:

  • Unusual vaginal bleeding or spotting (most common)
  • Vague pelvic discomfort
  • Generalized weakness
  • Unexplained weight loss


Made by tissue evaluation for pathologic confirmation by either endometrial biopsy or dilation and curettage (D&C).


  • Stage I: Cancer is confined to the uterus
  • Stage II: The cancer has extended to the cervix
  • Stage III: Extension of the tumor outside the uterus to other pelvic organs or lymph nodes
  • Stage IV: Metastasis (spread) beyond the uterus, pelvis and lymph nodes


  • Grade I: well-differentiated
  • Grade I: moderately-differentiated
  • Grade I: poorly-differentiated


Surgery is usually the treatment of choice and includes hysterectomy with removal of the fallopian tubes, ovaries and lymph nodes in the pelvis.

Recommended Follow-Up:

Routine Pelvic exams along with PAP smears to be scheduled as follows:

  • Every 3-4 months for 2 years
  • Every 6 months for 3-5 years
  • Yearly thereafter